Design, synthesis and antifungal activity of pterolactam-inspired amide Mannich bases
نویسندگان
چکیده
منابع مشابه
Antifungal activity studies of some mannich bases carrying nitrofuran moiety
A series of 3-substituted-4-(5-nitro-2-furfurylidene)amino-5-mercapto-1,2,4-triazoles 3 and their Mannich bases have been synthesized. The structures of these Schiff bases and Mannich bases were confirmed on the basis of elemental analysis, H NMR and mass spectral data. The above compounds were also screened for their antifungal activity against C.albicans.
متن کاملSYNTHESIS OF PARACETAMOL DERIVATIVES AS MANNICH BASES AND THEIR ANTIBACTERIAL ACTIVITY
Aim: A variety of Paracetamol derivatives as mannich bases were prepared through mannich reaction by reacting Paracetamol as compound containing active hydrogen, substituted benzaldehyde, morpholine as secondary amine compound and small amount of conc. HCl as catalyst. A simplistic one-pot method under mild conditions has been developed for the synthesis of all the compounds and they were chara...
متن کاملsynthesis and characterization of some macrocyclic schiff bases
ماکروسیکلهای شیف باز از اهمیت زیادی در شیمی آلی و دارویی برخوردار می باشند. این ماکروسیکلها با دارابودن گروه های مناسب در مکانهای مناسب می توانند فلزاتی مثل مس، نیکل و ... را در حفره های خود به دام انداخته، کمپلکسهای پایدار تولید نمایند. در این پایان نامه ابتدا یک دی آلدئید آروماتیک از گلیسیرین تهیه می شود و در مرحله بعدی واکنش با دی آمینهای آروماتیک و یا آلیفاتیک در رقتهای بسیار زیاد منجر به ت...
15 صفحه اولSynthesis and Biological Activity of Certain Mannich Bases Derivatives from 1, 2, 4-Triazoles
Substituted 1, 2, 4- Triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. These triazoles were used for preparation of different derivatives by two different schemes. In the first scheme the Mannich bases were prepared from 5- marcapto-s triazole Quinazolines. The 5-Marcato-s-Tr...
متن کاملsynthesis and biological activity of certain mannich bases derivatives from 1, 2, 4-triazoles
substituted 1, 2, 4- triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. these triazoles were used for preparation of different derivatives by two different schemes. in the first scheme the mannich bases were prepared from 5- marcapto-s triazole quinazolines. the 5-marcato-s-tr...
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ژورنال
عنوان ژورنال: Fitoterapia
سال: 2020
ISSN: 0367-326X
DOI: 10.1016/j.fitote.2020.104581